Camparative Study of the Physical Parameters in DMBA Induced Oral Carcinoma Rat Model and Herbal Extract FED Oral Carcinoma Rat Model
A. Shukla *
Department of Zoology, Government Arts and Commerce College, Rau, Indore, India.
V. K. Sharma
Government Holkar Science College, Indore (M.P), India.
*Author to whom correspondence should be addressed.
Abstract
Cancer, a multifactorial disorder, arises due to defect in genetic makeup and exposure to unfavourable environmental conditions. Oral cancer, a life-threatening cancer worldwide, arises in the oral cavity due to ill-habits such as tobacco smoking and chewing. Monitoring body weight is an essential aspect of any preclinical study, including DMBA-induced oral carcinoma rat models and models with potential therapeutic interventions like Zingiber and piper feeding. Changes in body weight, feeding, water intake can provide valuable insights into the general health and physiological effects of the experimental conditions.
Keywords: Body weight, squamous cell carcinoma, phytochemicals, Zingiber officinale, piper nigrum, DMBA