The Role of Sudden Weight Loss as an Early Indicator of Diabetes Onset in Prediabetic and Newly Diagnosed Diabetic Patients
Tyas Anggraini *
Faculty of Medicine, Dian Nuswantoro University, Semarang, Indonesia.
Slamet Isworo
Faculty of Health, Dian Nuswantoro University, Semarang, Indonesia.
Enny Rachmani
Faculty of Health, Dian Nuswantoro University, Semarang, Indonesia.
Cynthia Arsita
Faculty of Medicine, Dian Nuswantoro University, Semarang, Indonesia.
Rahel Amanda Konoralma
Faculty of Medicine, Dian Nuswantoro University, Semarang, Indonesia.
Andreas Wilson Setiawan
Faculty of Medicine, Dian Nuswantoro University, Semarang, Indonesia.
Lely Kusumaningrum
Faculty of Medicine, Dian Nuswantoro University, Semarang, Indonesia.
Surya Ayu Pratiwi
Faculty of Medicine, Dian Nuswantoro University, Semarang, Indonesia.
Daffa Zaedan Hanif
Faculty of Medicine, Dian Nuswantoro University, Semarang, Indonesia.
Iksa Yoda Paksi
Faculty of Medicine, Dian Nuswantoro University, Semarang, Indonesia.
Ni Komang Widnyan
Faculty of Medicine, Dian Nuswantoro University, Semarang, Indonesia.
*Author to whom correspondence should be addressed.
Abstract
Background and Objective: Sudden weight loss is a potential early indicator of metabolic disorders commonly associated with diabetes, although its role in the early detection of the disease has not been extensively studied. Therefore, further exploration is needed to evaluate whether unexplained weight loss can serve as a more significant risk factor or marker for early diabetes detection, as well as to understand the metabolic changes occurring in the body of individuals with diabetes. This study investigates the relationship between unexplained sudden weight loss and early diagnosis of diabetes in prediabetic patients and newly diagnosed diabetic patients.
Methods: This research employed a cross-sectional observational design, analyzing the association between sudden weight loss and a diabetes diagnosis using statistical tools such as SPSS.
Results: The findings revealed a statistically significant relationship, as indicated by a p-value of 0.001 and an odds ratio of 8.39, suggesting that individuals experiencing unexplained weight loss are eight times more likely to be diagnosed with diabetes.
Discussion: These results suggest that sudden weight loss may serve as an important diagnostic clue in identifying individuals at risk for diabetes at an early stage, particularly in high-risk populations.
Conclusion: The findings support the need for healthcare providers to consider unexplained weight loss as a potential warning sign for the onset of diabetes, prompting earlier screening and intervention.
Keywords: Sudden weight loss, early diabetes diagnosis, prediabetic patients, metabolic disorders, screening and intervention