Asian Journal of Biochemistry, Genetics and Molecular Biology

This review aims to examine the use of Mitracarpus scaber and Ageratum conyzoides in the traditional management of eczema in Nigeria, with an emphasis on their bioactive compounds. Various medicinal plants are used globally in the treatment of different skin diseases such as eczema, skin rashes, ringworm, vitiligo, measles, boils, chicken pox, and small pox. Herbal medicine is as old as civilization. Usage of herbal medicine is common among the low income-groups in villages across West Africa countries where medicinal services are less accessible. Herbal treatments are generally perceived as effective with few side effects. Eczema is a condition that causes dry and itchy patches of the skin. The condition weakens the skin’s barrier function, which is responsible for helping the skin to retain moisture and protecting the body from outside elements. Management of the condition is complicated. Mitracarpus scaber and Ageratum conyzoides have been reported in the treatment of various skin diseases prominent among which is eczema. The use of these plants for treating the disease has gained so much attention to the extent that, they are now being formulated into antifungal cream. This review explores the bioactive compounds of these plants and their potentials in managing the condition.