Prevalence of Hyperuricemia in the Biochemistry Laboratory of Aristide Le Dantec Hospital
Gueye Mouhamadou Moustapha *
Biochemistry Laboratory, Aristide Le Dantec Hospital, Senegal.
Soumah Idrissa Yahya
Biochemistry Laboratory, Aristide Le Dantec Hospital, Senegal and Medical Biochemistry Laboratory, Faculty of Medicine, Pharmacy and Odontology (FMPO), Cheikh Anta Diop University of Dakar, Senegal.
Samba Abdourahmane
Medical Biology Analysis Laboratory, Abass Ndao Hospital, Senegal.
FAYE Ibrahima
Biochemistry Laboratory, Aristide Le Dantec Hospital, Senegal.
Sow Harouna Ousmane
Department of Biological Hematology and Oncology-Hematology (HBOH), Faculty of Medicine, Pharmacy and Odontology (FMPO/FMPOS), Cheikh Anta Diop University of Dakar (UCAD), Dakar, Senegal.
Lo Serigne Adoul Ahad
Biochemistry Laboratory, Aristide Le Dantec Hospital, Senegal.
Cissé Moussa
Urology department, Dalal Jam Hospital, Senegal.
Diedhiou Fatou
Biochemistry Laboratory, Aristide Le Dantec Hospital, Senegal.
Ba Ramatoulaye
Biochemistry Laboratory, Dalal Jamm Hospital, Senegal.
Dia Sy Fatou Kine Thorpé
Biochemistry Laboratory, Dalal Jamm Hospital, Senegal.
Coly Nadja Fatou
Biochemistry Department, Iba Der Thiam University of Thiès, Senegal.
Diouf Niokor
Biochemistry Department, Assane Seck University of Ziguinchor, Senegal.
Doupa Dominique
Biochemistry Department, Gaston Berger University of Saint-Louis, Senegal.
Ndiaye Arame
Biochemistry Laboratory, Aristide Le Dantec Hospital, Senegal and Medical Biochemistry Laboratory, Faculty of Medicine, Pharmacy and Odontology (FMPO), Cheikh Anta Diop University of Dakar, Senegal.
Cisse Fatou
Medical Biochemistry Laboratory, Faculty of Medicine, Pharmacy and Odontology (FMPO), Cheikh Anta Diop University of Dakar, Senegal and Biochemistry Laboratory, Dalal Jamm Hospital, Senegal.
Diatta Alassane
Biochemistry Department, Assane Seck University of Ziguinchor, Senegal.
Souleymane Thiam
Medical Biochemistry Laboratory, Faculty of Medicine, Pharmacy and Odontology (FMPO), Cheikh Anta Diop University of Dakar, Senegal and Biochemistry Laboratory, Dalal Jamm Hospital, Senegal.
Agne Diallo Fatou
Biochemistry Laboratory, Aristide Le Dantec Hospital, Senegal and Medical Biochemistry Laboratory, Faculty of Medicine, Pharmacy and Odontology (FMPO), Cheikh Anta Diop University of Dakar, Senegal.
*Author to whom correspondence should be addressed.
Abstract
Introduction: Hyperuricemia is a common biochemical abnormality associated with several pathologies such as chronic kidney disease, arterial hypertension, and cardiovascular diseases. The aim of our study was to determine the prevalence of hyperuricemia among hospitalized patients at Aristide Le Dantec Hospital.
Methodology: This was a retrospective study covering the period from January 4, 2021, to January 4, 2022, focusing on serum samples from hospitalized patients sent to the biochemistry laboratory of Aristide Le Dantec University Hospital for blood uric acid measurement. Uric acid assay was performed on the ARCHITECT ci4100 analyzer (Abbott). Data were collected from the registry of results for hospitalized patients and processed using Microsoft Excel 2013.
Results: Our study included 444 patients aged from 10 days to 88 years, with a mean age of 42 years and a male-to-female sex ratio of 1.27. The prevalence of hyperuricemia in our population was 61.03%, with a higher frequency among patients aged 61 to 80 years (37.63%). 53.03% of hyperuricemia cases originated from the cardiology department, followed by pediatric oncology (26.20%). The prevalence of hyperuricemia in cardiovascular diseases was 68.45%, 57.04% in cancer patients, 86.7% in renal diseases, and 75% in patients with pre-eclampsia.
Conclusion: At the end of our study, we observed a high prevalence of hyperuricemia, more frequent in cardiovascular pathologies, followed by cancers and renal diseases.
Keywords: Hyperuricemia, cardiovascular diseases, HALD (Hôpital Aristide Le Dantec)